Mix Cornmeal, Paprika, Onion Powder, Garlic Powder, And Cayenne Pepper On A Plate. Beat Milk And Eggs Together In A Bowl. Dip Catfish Fillets In Milk Mixture, Then Gently Press Fillets Into Cornmeal Mixture, Coating Both Sides. Shake Off Excess Breading. Heat Vegetable Oil In A Large Skillet; Pan-Fry Catfish In Hot Oil Until The Fish Is Golden Brown And Flakes Easily With A Fork, About 4 Minutes Per Side.